- Product Details
Keywords
- MGF (Mechano Growth Factor)
- MGF
- Mechano Growth Factor
Quick Details
- ProName: MGF
- Molecular Formula: C121H200N42O39
- Appearance: Lyophilzed white powder
- Application: Research use only
- ProductionCapacity: Metric Ton/Day
- Purity: 98%
- Storage: -20℃
- LimitNum: 0 Metric Ton
Superiority
Sequence:
H-Tyr-Gln-Pro-Pro-Ser-Thr-Asn-Lys-Asn-Thr-Lys-Ser-Gln-Arg-Arg-Lys-Gly-Ser-Thr-Phe-Glu-Glu-His-Lys-NH2
FM: C121H200N42O39
MW: 2867.14
Storage: Store at -20C. Keep container tightly closed. Store in a cool dry place.
Appearance: Lyophilzed white powder
Details
Mechano Growth Factor (MGF) with sequence YQPPSTNKNTKSQRRKGSTFEEHK-NH2, is a novel splice variant of the insulin growth factor -1 (IGF-1), also known as IGF-1Ec in humans and IGF-1Eb in rodents. Studies have suggested that MGF plays a number of physiological roles because the failure in its expression may result to age-related loss of skeletal function. One included in its functions is its ability to become a potent neuroprotective as supported by the study that has shown functional copies of the MGF cDNA to be expressed in a plasmid vector which then protected facial neurons after nerve damage. One such failure is called sarcopenia. The appearance of MGF also initiates the upregulation of new protein synthesis.